Think about it, it makes sense. Dre was not very involved in Recovery or MMLP2, so Eminem is upset at him for leaving. The song is Eminem venting about Dr. Dre leaving him, while trying to mask it as another women song so that he doesn't directly rip into Dre in public.
It makes total sense, let's not forget that Dr. Dre signed Eminem on November 31st, that would have been their "anniversary". Dre must have stopped working with Eminem frequently on the 1st of May.
The "it was almost a homicide" line refers to Eminem almost murdering Dre's career for him leaving, but then decided to make this song is disguise so that Dre could still be a rapper.
It makes sense when you think about it.